Title

Triterpenoid Saponins From Sesbania vesicaria (Abstract)

Authors

Wei Yuan, Stephen F Austin State University, Arthur Temple College of Forestry and AgricultureFollow
Ping Wang, Stephen F Austin State University, Arthur Temple College of Forestry and AgricultureFollow
Zhizhen Zhang
Zushang Su, Stephen F. Austin State University, Arthur Temple College of Forestry and AgricultureFollow
Shiyou Li, Stephen F Austin State University, Arthur Temple College of Forestry and AgricultureFollow

Document Type

Article

Publication Date

2-2013

Abstract

Nine oleanane saponins including three new and six known were isolated from the seeds of Sesbania vesicaria. The new saponins were established as 3-O-[α-l-rhamnopyranosyl-(1 → 3)]-β-d-glucuronopyranosyl-3β,29-dihydroxy-olean-12-en-28-oic acid, 3-O-α-l-rhamnopyranosyl-28-O-β-d-glucopyransoyl-3β-hydroxy-olean-12-en-23-al-28-oate, and 3-O-α-l-rhamnopyranosyl-28-O-β-d-glucopyransoyl-3β,23-dihydroxy-olean-12-en-28-oate. All isolated saponins were assayed for their DNA topoisomerase I inhibition ability and cytotoxicity against A549 human lung adenocarcinoma epithelial cells with no positive activity detected (IC₅₀ > 312 μM and GI₅₀ > 25 μM, respectively).

Comments

Originally Published in Phytochemistry Letters (2013) 6(1): 106-109 doi:10.1016/j.phytol.2012.11.003

Subscribers may access full text here

Repository Citation

Yuan, Wei; Wang, Ping; Zhang, Zhizhen; Su, Zushang; and Li, Shiyou, "Triterpenoid Saponins From Sesbania vesicaria (Abstract)" (2013). NCPC Publications and Patents. 40.
https://scholarworks.sfasu.edu/ncpc_articles/40