The infectivity of a coccidiosis vaccine and its ability to immunize chickens against two species of Eimeria was examined. The vaccine was administered to newly-hatched chicks by spraying directly onto the eye. The method resulted in a high proportion of chicks infected with E. acervulina and E. tenella. Vaccinated birds reared in cages in the absence of reinfection did not develop immunity to either species by 4 wk of age, but birds reared in floor pens developed immunity to both E. acervulina and E. tenella.
Chapman, H. David and Cherry, Tim E., "Eyespray Vaccination: Infectivity and Development of Immunity to Eimeria acervulina and Eimeria tenella" (1997). Faculty Publications. 20.
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