Document Type

Article

Publication Date

1999

Abstract

Sodium arsenite (NaAsO2), at 10% of its median lethal dose, was administered to rats with and without vitamin C pretreatment. Liver microsomal fraction was isolated and the activity of Ca2+-ATPase was assayed. Sodium arsenite was found to inhibit the activity of the liver microsomal Ca2+-ATPase to 50% to that of control rats. The specific activity of the enzyme in rats administered sodium arsenite with vitamin C pretreatment was not significantly different from that of control rats.

Comments

Odunuga, OO., Okunade, WG., & Olorunsogo, OO (1999), Reversal of sodium arsenite inhibition of rat liver microsomal Ca2+ pumping ATPase by vitamin C. Bioscience Reports 19: 11-15

Share

COinS

Tell us how this article helped you.